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Literature summary extracted from

  • Li, M.S.; Monahan, I.M.; Waddell, S.J.; Mangan, J.A.; Martin, S.L.; Everett, M.J.; Butcher, P.D.
    cDNA-RNA subtractive hybridization reveals increased expression of mycocerosic acid synthase in intracellular Mycobacterium bovis BCG (2001), Microbiology, 147, 2293-2305.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.111 eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ Mycobacterium tuberculosis fatty acid biosynthesis tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.111 Mycobacterium tuberculosis
-
 var. bovis Bacillus Calmette-Guerin
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6.2.1.49 Mycobacterium tuberculosis variant bovis Q02278
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.111
-
 Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.111 eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+
-
 Mycobacterium tuberculosis tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
-
 ?
2.3.1.111 eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ fatty acid biosynthesis Mycobacterium tuberculosis tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.2.1.49 fadD28
-
 Mycobacterium tuberculosis variant bovis